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STEMCELL Technologies Garcinol

Product Code. 17110072
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 17110072

Brand: STEMCELL Technologies 72452

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This item is not returnable. View return policy

Description

Epigenetic modifier; Inhibits histone acetyltransferases (HAT) p300 and pCAF

  • Garcinol is an inhibitor of histone acetyltransferases (HATs) p300 and pCAF (IC50 = 7 and 5 μM, respectively) (Balasubramanyam et al.) It also inhibits the HAT GCN5 in Cryptococcus neoformans, inducing temperature sensitivity and impairing growth (O'Meara et al.)
  • Promotes ex vivo expansion of human hematopoietic stem cells (Nishino et al.)
  • Promotes neurogenesis in rat cortical progenitor cells (Weng et al.)
  • Induces apoptosis in several types of cancer cells and has anti-inflammatory actions (Koeberle et al.; Prasad et al.)

Specifications

CAS 78824-30-3
Synonym Camboginol
Quantity 5 mg
Molecular Formula C38H50O6
Purity ≥95%
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