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  6. TdB Labs AB FITC-CM-dextran Green Fluorophore

TdB Labs AB FITC-CM-dextran Green Fluorophore

Product Code. 30216288
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Molecular Weight (g/mol):
150 kDa
20 kDa
Quantity:
100 mg
1 g
Unit Size:
100mg
1g
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Product Code. 30216288

Brand: TdB Labs AB FCMD150_100mg

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This item is not returnable. View return policy

Description

FITC-CM-dextran 150 kDa is a high molecular weight, green-fluorescent, carboxymethylated dextran. It is ideal for studying macromolecular transport, permeability, and diffusion in complex biological systems.

  • Product Overview: FITC-CM-dextrans are carboxymethylated dextrans conjugated with fluorescein isothiocyanate (FITC), providing a stable, green fluorescent polysaccharide ideal for permeability studies, molecular tracking, and bioimaging. The carboxymethyl groups improve solubility and biocompatibility, while the FITC labeling allows sensitive detection using standard fluorescence instrumentation. Available in multiple molecular weights, the FITC-CM-Dextran series is tailored for a wide range of biological and analytical applications.
  • Features:
    • Stable Green Fluorescence: FITC fluorophore provides excitation at 495 nm and emission at 519 nm, ideal for use with common FITC filter sets.
    • Carboxymethylation for Enhanced Solubility: Carboxymethyl groups increase water solubility and improve the biocompatibility of the dextran backbone.
    • Available in a Wide Range of Molecular Weights: Offered in standard sizes such as 4 kDa, 20 kDa, 40 kDa, 70 kDa, and 150 kDa to match diffusion, permeability, and transport study needs.
    • Water-Soluble and Biocompatible: Ready for use in biological assays without organic solvents or extensive preparation steps.
    • Lot-to-Lot Consistency: Manufactured under controlled conditions to ensure reproducible fluorescence intensity, substitution degree, and molecular weight distribution.
  • Benefits:
    • Accurate Tracking of Molecular Movement: Enables sensitive tracing of molecules in fluid flow, tissue penetration, and cellular transport experiments.
    • Optimized for Permeability Studies: Commonly used to assess barrier integrity in epithelial and endothelial models, including blood-brain barrier, gut, and vascular research.
    • Ideal for Bioimaging: Provides bright, stable fluorescence for visualization of molecular transport and diffusion processes.
    • Flexible Application Range: Multiple molecular weights allow researchers to study size-dependent effects in transport and permeability.
    • Low Cytotoxicity: Suitable for live-cell imaging and tissue experiments without significant impact on biological systems.
  • Applications:
    • Barrier Integrity Studies: Used to measure transport across tight junctions in epithelial, endothelial, and engineered tissues.
    • Fluid Flow and Diffusion Tracking: Applied in microfluidic devices, perfusion systems, and tissue models to visualize molecular movement.
    • Live and Fixed Cell Imaging: Suitable for dynamic live-cell experiments as well as endpoint imaging following fixation.
    • Size Exclusion Research: Used to study molecular cutoff properties of biological membranes and engineered systems.
    • Bioengineering and Tissue Engineering: Supports analysis of engineered tissue constructs, including permeability and nutrient transport studies.
  • Technical Specifications:
    • Fluorescence: Excitation maximum at 495 nm, emission maximum at 519 nm.
    • Molecular Weights: Available at 4 kDa, 20 kDa, 40 kDa, 70 kDa, and 150 kDa standard options.
    • Degree of Labeling: Controlled within defined ranges to optimize brightness while preserving dextran behavior.
    • Appearance: Supplied as a light-sensitive, greenish powder, fully soluble in water.
  • Storage and Stability:
    • Store dry and protected from light at 2°C to 8°C for best stability.
    • Stable under recommended conditions for extended storage periods without significant loss of fluorescence.
  • Packaging and Availability:
    • Supplied as dry powder for maximum shelf life and handling flexibility.
    • Available in various packaging sizes to support small-scale research and larger experimental workflows.

Specifications

Quantity 100 mg
Product Type Fluorescent Labeling Reagent
Molecular Weight (g/mol) 150 kDa
Label Type Other Labels or Dyes
Color Green
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