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Thermo Scientific™ EZ-Link™ Amine-PEG3-Biotin

Product Code. 11881215 Shop All Thermo Scientific Products
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Quantity:
50 mg
Unit Size:
50mg
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11881215 50 mg 50mg
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Product Code. 11881215 Supplier Thermo Scientific™ Supplier No. 21347

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Description

Biotinylate proteins or surfaces using EDC or other amine-reactive crosslinkers with a mid-length (22.9A) biotinylation reagent containing a 3-unit polyethylene glycol spacer.

Thermo Scientific™ EZ-Link Amine-PEG3-Biotin is a biotinylation reagent that contains a 3-unit polyethylene glycol (PEG) spacer arm and a terminal primary amine for conjugation and protein labeling with EDC or other crosslinkers.

Amine-PEG2-Biotin is a water-soluble biotin compound containing polyethylene glycol (PEG) spacer arm and a terminal primary amine. The hydrophilic PEG spacer arm imparts water solubility that is transferred to molecules that are conjugated to the biotin compound. The PEG spacer arm also gives this reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules. The amine group of this amine-PEG-biotin compound can be reacted with the crosslinker EDC to form conjugates with carboxylates and 5' phosphates.

Highlights:

  • Use the EDC crosslinker to couple this analog to carboxyl (-COOH) groups or 5' phosphate groups
  • Water-soluble, polyethylene glycol (PEG) spacer arm
  • Longer chain length for reduction of steric hindrance
  • PEG spacer arm transfers hydrophilicity to final conjugate
TRUSTED_SUSTAINABILITY

Specifications

Product Type Amine-PEG3-Biotin
Quantity 50 mg
Content And Storage Store at 4°C.
Product Line EZ-Link
Cell Permeability Cell-Impermeant
Chemical Reactivity Carboxylic Acid, Ketone, Aldehyde
Reactive Moiety Amine
Solubility Water
Label or Dye Biotin
Spacer Mid-length, Pegylated
Label Type Biotin & Analogs
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Safety and Handling

compliance-icons
Product Identifier
  • EZ-Link Amine-PEG3-Biotin
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P403+P233-Store in a well-ventilated place. Keep container tightly closed.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : EZ-Link Amine-PEG3-Biotin

For Research Use Only. Not for use in diagnostic procedures.

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