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Tocris Bioscience™ EMPA
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Product Code. 30001565
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001565

Brand: Tocris Bioscience™ 4558/50

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Description

Highly potent and selective OX2 antagonist; brain penetrant

Highly potent, selective OX2 receptor antagonist (IC50 values are 2.3 nM and 1900 nM for OX2 and OX1 respectively). Displays negligible or no inhibition of a panel of 80 receptors. Blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 values are 7.9 nM and 8.8 nM respectively); reverses orexin-B-induced hyperlocomotion in mice. Brain penetrant.
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Chemical Identifiers

CAS 680590-49-2
Molecular Formula C23H26N4O4S

Specifications

Quantity 50 mg
Formula Weight 454.54
Purity >98%
Molecular Weight (g/mol) 454.545
Chemical Name or Material EMPA
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