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DL-Thioctic acid, 98%, Thermo Scientific™
DL-Thioctic acid, CAS # 1077-28-7, is an antioxidant and coenzyme important for the activity of enzymes.
Marke: Thermo Scientific Alfa Aesar L04711.06
| Quantity | 5g |
|---|
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Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• DL-Thioctic acid derives from octanoic acid, and it has been described as an antioxidant coenzyme important for the activity of enzyme complexes including pyruvate dehydrogenase and glycine decarboxylase
Application
• DL-Thioctic acid has been used in in vivo studies to increase insulin sensitivity and stimulate glucose uptake into adipose and muscle cells in vitro
• DL-Thioctic acid has an essential role in aerobic metabolism
• It has been used as free radical scavenger compound
• It can also assist in repairing oxidative damage via the increase of endogenous antioxidants, including vitamins C, vitamin E, and glutathione
• It can induce apoptosis through caspase-independent and caspase-dependent pathways, a process mediated by intracellular Ca2+
• DL-Thioctic acid has the ability to impact various cellular biological pathways since it can increase glutathione synthesis and modulate transcription factor activity, mainly nuclear factor kappa B (NF-κB)
• It can decrease the phagocytosis of myelin by macrophages
Chemische Identifikatoren
| C8H14O2S2 | |
| MFCD00005474 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| CHEBI:16494 | |
| OC(=O)CCCCC1CCSS1 |
Spezifikation
| 1077-28-7 | |
| C8H14O2S2 | |
| 5g | |
| 14,9326 | |
| Soluble in methanol,ethanol,diethyl ether and chloroform. Insoluble in water. | |
| OC(=O)CCCCC1CCSS1 | |
| 206.32 | |
| CHEBI:16494 | |
| 98% |
| 160°C to 165°C | |
| MFCD00005474 | |
| 81853 | |
| dl-thioctic acid, thioctic acid, alpha-lipoic acid, 5-1,2-dithiolan-3-yl pentanoic acid, dl-alpha-lipoic acid, 1,2-dithiolane-3-pentanoic acid, 6,8-thioctic acid, thioctacid, 6-thioctic acid, alpha lipoic acid | |
| AGBQKNBQESQNJD-UHFFFAOYNA-N | |
| 5-(1,2-dithiolan-3-yl)pentanoic acid | |
| 864 | |
| 206.33 | |
| DL-Thioctic acid |
Sicherheit und Handhabung
Produktidentifikator
Signalwort
Gefahrenkategorie
Gefahrenhinweis
Sicherheitshinweis
Ergänzende Informationen
- DL-Thioctic acid
Signalwort
- Warning
Gefahrenkategorie
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
Gefahrenhinweis
- H302-Harmful if swallowed.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Sicherheitshinweis
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P337+P313-If eye irritation persists: Get medical advice/attention.
Ergänzende Informationen
- MIXTURE LIST-Contain: DL-Thioctic acid
Name des Produkts
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