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R&D Systems™ Dasatinib

Product Code. 18708146
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Quantity:
100 mg
Unit Size:
100mg
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18708146 100 mg 100mg
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Product Code. 18708146 Supplier R&D Systems™ Supplier No. 6793/100
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    181.00€
    171.15€ / 100mg
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Estimated Shipment: 29-10-2026
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Description

A Tocris product, part of R&D Systems. Highly potent pan-Src/Bcr-Abl inhibitor

Dasatinib is a highly potent pan-Src/Bcr-Abl inhibitor (Ki values are 16 and 30 pM, respectively. Inhibits Bcr-Abl, Src, Lck, Fyn, c-kit and Yes with IC50 values in the subnanomolar range. Inhibits proliferation of tumor cells in vitro and exhibits anticancer acivity in vivo in a mouse chronic myelogenous leukemia (CML) xenograft model. Inhibits replication of SARS-CoV and MERS-CoV in vitro (EC50 values are 2.1and 5.5 μM, respectively). Dasatinib also enhances CD3-targeted lentiviral vector-mediated gene transfer by 3 to 10-fold.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
CAS 302962-49-8
Synonym BMS-354825
Quantity 100 mg
Product Line Tocris
Molecular Formula C22H26ClN7O2S
Formula Weight 488.01
Purity 98%
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