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Tocris Bioscience™ CPI 203
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Product Code. 18758188
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 18758188

Brand: Tocris Bioscience™ 5331/10

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This item is not returnable. View return policy

Description

BET bromodomain inhibitor; arrests cell cycle at G1 phase

CPI 203 is a BET bromodomain inhibitor. Downregulates Myc expression, causes G1 cell cycle arrest and attenuates cell proliferation in human pancreatic neuroendocrine tumors. Arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Also enhances the antitumor effect of rapamycin (Cat. No. 1292) in vitro and attenuates rapamycin induced Akt activation. Also enhances fibroblast reprogramming to hiPSCs at low concentration. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type CPI 203
Purity >98%
Molecular Weight (g/mol) 399.9
Inhibitors CPI 203

For Research Use Only

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