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  5. Tocris Bioscience™ Conduritol B epoxide

Tocris Bioscience™ Conduritol B epoxide
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Product Code. 18718546
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25 mg
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18718546 25 mg 25mg
18788696 5 mg 5mg
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Product Code. 18718546 Supplier Tocris Bioscience™ Supplier No. 7056/25

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514.20 EUR valid until 2026-03-31
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Description

Irreversible glucocerebrosidase (β-glucosidase) inhibitor; used to generate Gaucher disease models

Conduritol B epoxide is an irreversible glucocerebrosidase (GBA) inhibitor (Ki = 53 μM; IC50 = 4.28 - 9.49 μM). Also inhibitis lysosomal α-glucosidase. Used to generate animal models of Gaucher disease. Accelerates recovery of peripheral nerve injury in mice. Preserves motoneurons and ganglioside distribution at the neuromuscular junction, delays disease onset and improves motor function in a mouse ALS model.
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Specifications

Chemical Name or Material DL-1,2-Anhydro-myo-Inositol
CAS 6090-95-5
Quantity 25 mg
Target Glycosylase Inhibitors
Molecular Formula C6H10O5
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