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Tocris Bioscience™ CNQX
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Product Code. 30001060
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50 mg
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Product Code. 30001060 Supplier Tocris Bioscience™ Supplier No. 0190/50

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Description

Potent and selective non-NMDA iGluR antagonist

CNQX is an AMPA and kainate receptor antagonist (IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively). CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM). CNQX can be used to isolate GABAA receptor-mediated spontaneous inhibitory postsynaptic currents and antagonizes non-NMDA receptor-mediated responses in cultured cerebellar granule cells. CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.

CNQX Disodium Salt (Cat. No. 1045) also available.

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Chemische Identifikatoren

CAS 115066-14-3
Molecular Formula C9H4N4O4

Spezifikation

Quantity 50 mg
Formula Weight 232.16
Purity >99%
Molecular Weight (g/mol) 232.155
Chemical Name or Material CNQX
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