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Thermo Scientific Chemicals Citrate, 0.5M buffer soln., pH 3.0
Description
Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.
Solubility
Fully miscible in water. Insoluble in ethanol.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
Specifications
| Color | Colorless |
| Concentration | 0.5M buffer soln. |
| Molecular Weight (g/mol) | 294.10 |
| pH | 3.0 |
| Quantity | 250 mL |
| Odor | Odorless |
| Content And Storage | Keep cold |
| Form | Liquid |
RUO – Research Use Only