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  5. R&D Systems™ Ciliobrevin A

R&D Systems™ Ciliobrevin A

Product Code. 18745706
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5 mg
25 mg
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Product Code. Quantity Unit Size
18745706 5 mg 5mg
18719026 25 mg 25mg
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Product Code. 18745706 Supplier R&D Systems™ Supplier No. 4529/5
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Estimated Shipment: 29-10-2026
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Description

A Tocris product, part of R&D Systems. Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein

Ciliobrevin A is a Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo. Perturbs primary cilia formation; inhibits cytoplasmic AAA+ ATPase dynein-dependent microtubule gliding and ATPase activity.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile
CAS 302803-72-1
Assay Percent Range >98%
Quantity 5 mg
Product Line Tocris
Molecular Formula C17H9Cl2N3O2
Formula Weight Observed MW: 358.18
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