missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Lines and Blood Products
  4. Cell Lines and Cell Cultures
  5. General Cell Lines and Cell Cultures
  6. 17315089

DiscoverX ChemiScreen™ V1A Vasopressin Receptor Stable Cell Line

Product Code. 17315089
Encompass
Change view
Click to view available options
Quantity:
2 Vials
Unit Size:
2 ampoules
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
17315089 2 Vials 2 ampoules
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 17315089 Supplier DiscoverX Supplier No. HTS059C

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

The ChemiScreen™ V1A Vasopressin Receptor Stable Cell Line measures AVPR1A (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.

The ChemiScreen™ V1A Vasopressin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR1A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR1A alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR1A , the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Calcium Flux
Cell Line Chem-1
For Use With (Application) Cell Lines
Primary Agonist [Arg8]-Vasopressin Acetate
Quantity 2 Vials
Target Entry AVPR1A
Accession Number NM_000706.3
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.