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STEMCELL Technologies CAY10603

Product Code. 17190242
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1 mg
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Product Code. 17190242 Supplier STEMCELL Technologies Supplier No. 73582

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Description

Epigenetic modifier; Inhibits histone deacetylase (HDAC) 6

  • CAY10603 is a selective and potent inhibitor of histone deacetylase 6 (HDAC6; IC50 = 0.002 nM; Kozikowski et al.) HDAC6 deacetylates lysine residues on the N-terminal part of histones
  • HDAC6 is also known to regulate heat shock protein 90 (hsp90) via hyperacetylation (Rao et al.)
  • Inhibits growth of several pancreatic cancer cell lines (IC50 = 0.1 - 1 μM) and SCCOHT, an ovarian cancer cell line (Kozikowski et al.; Wang et al.)

Specifications

CAS 1045792-66-2
Synonym HDAC6 inhibitor
Quantity 1 mg
Molecular Formula C22H30N4O6
Purity ≥95%
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