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DiscoverX cAMP Hunter™ CHO-K1 MC3R Gs Cell Line

Product Code. 17314449
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17314449

Brand: DiscoverX 950045C2

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This item is not returnable. View return policy

Description

The cAMP Hunter™ CHO-K1 MC3R Gs Cell Line measures MC3R (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

The cAMP Hunter MC3R Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-melanocyte stimulating hormone) based activation of MC3R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype MC3R , a naturally Gs coupled GPCR. Upon activation of MC3R , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Intracellular cAMP level
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist α-Melanocyte stimulating hormone
Quantity 2 Vials
Target Entry MC3R
Accession Number AY227893
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