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DiscoverX cAMP Hunter™ CHO-K1 HRH2 Gs Cell Line

Product Code. 17354439
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Quantity:
2 Vials
Unit Size:
2 ampoules
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17354439 2 Vials 2 ampoules
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Product Code. 17354439 Supplier DiscoverX Supplier No. 950043C2

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Description

The cAMP Hunter™ CHO-K1 HRH2 Gs Cell Line measures HRH2 (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

The cAMP Hunter HRH2 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. histamine) based activation of HRH2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype HRH2 , a naturally Gs coupled GPCR. Upon activation of HRH2 , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Intracellular cAMP level
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist Histamine
Quantity 2 Vials
Target Entry HRH2
Accession Number AY136744
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