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DiscoverX cAMP Hunter™ CHO-K1 ADCYAP1R1 (PAC1) Gs Cell Line

Product Code. 17344499
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17344499

Brand: DiscoverX 950064C2

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This item is not returnable. View return policy

Description

The cAMP Hunter™ CHO-K1 ADCYAP1R1 (PAC1) Gs Cell Line measures ADCYAP1R1 (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

The cAMP Hunter ADCYAP1R1 (PAC1) Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PACAP) based activation of ADCYAP1R1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype ADCYAP1R1 , a naturally Gs coupled GPCR. Upon activation of ADCYAP1R1 , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Intracellular cAMP level
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist PACAP (1-27)
Quantity 2 Vials
Target Entry ADCYAP1R1 (PAC1)
Accession Number AY366498
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