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TheraPure™ Bz-dC Phosphoramidite, 20-400 finish bottle

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Product Code. 30054600 Supplier Thermo Scientific Supplier No. 27203284

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Description

Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis.

DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product. Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide. The TheraPure trademark denotes a highest level of phosphoramidite purity, developed with the highest stringency of of high definition analytics and tightly controlled impurity profiles. Ideal for any therapeutic application. This product is supplied in a 60 mL Amber bottle with a 20-400 Finish neck style, which is compatible with most Expedite Systems of oligonucleotide synthesizers.

Features:

  • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula—C46H52N5O8P
  • Base—dC
  • Base Protection—Bz
  • Formula weight—833.93 g/mol
  • CAS number—102212-98-6
  • HPLC Purity—≥99%; M-11 Impurity ≤0.01%; Single critical impurity ≤0.3%; Presence of dA, dG, or T impurity ≤0.03%
  • 31P NMR Purity—≥99%; Sum of non-primary peaks at 140-152 ppm: ≤0.3%; No peak(s) above 170 ppm; HMT impurity (∼146ppm): ≤0.10%
TRUSTED_SUSTAINABILITY

Specifications

Format Powder
For Use With (Equipment) Expedite Synthesizers
Product Type Bz-dC CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Deoxycytidine (dC)
Shipping Condition Room Temperature
Purity 99%
Quantity 1 bottle
Reagent Type Phosphoramidite
Grade TheraPure™
Nucleic Acid Type DNA
Product Line TheraPure
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For Research Use Only. Not for use in diagnostic procedures.

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