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  5. 18701849

BMX-IN-1
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Product Code. 18701849
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. 18701849

Brand: Tocris Bioscience 5123/5

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Description

Potent and irreversible BMX inhibitor

BMX-IN-1 is a potent and irreversible BMX inhibitor (IC50 = 25 nM). Covalently modifies Cysteine 496. Demonstrates selectivity over other Tec family members with identically positioned reactive cysteine residue in vitro. Reduces cell number and induces apoptosis in prostate cancer cell lines. Also inhibits proliferation and reduces viability in HeLa and SiHa cell lines.
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Specifications

Chemical Name or Material N-[2-Methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-2-propenamide
CAS 1431525-23-3
Assay Percent Range >98%
Quantity 5 mg
Molecular Formula C29H24N4O4S
Formula Weight Observed MW: 524.59
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