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R&D Systems™ BMS 299897
Description
Orally active, potent γ-secretase inhibitor (IC50 = 12 nM). Inhibits Aβ40 and Aβ42 formation in vitro (IC50 values are 7.4 and 7.9 nM respectively) and reduces Aβ in the brain, plasma and cerebrospinal fluid in vivo. Exhibits no Notch toxicity. Brain penetrant.
Specifications
Specifications
| CAS | 290315-45-6 |
| Quantity | 10 mg |
| Product Line | Tocris |
| Molecular Formula | C24H21ClF3NO4S |
| Formula Weight | 511.94 |
| Purity | >98% |
| Molecular Weight (g/mol) | 511.94 |
| Chemical Name or Material | BMS 299897 |
Product Title
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