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  7. Bisindolylmaleimide 1, Thermo Scientific Chemicals

Bisindolylmaleimide 1, Thermo Scientific Chemicals

Product Code. 15475649
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Product Code. 15475649 Supplier Thermo Scientific Alfa Aesar Supplier No. J63401.#0
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Description

Very potent and selective inhibitor of protein kinase C

Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.

Solubility
Insoluble in water.

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 133052-90-1
Molecular Formula C25H24N4O2
Molecular Weight (g/mol) 412.493
MDL Number MFCD00236428
InChI Key QMGUOJYZJKLOLH-UHFFFAOYSA-N
Synonym bisindolylmaleimide i, unii-l79h6n0v6c, rbt205 inhibitor, gö 6850, bisindolylmaleimide i gf 109203x, bim-1, chembl7463, 2-1-3-dimethylaminopropyl indol-3-yl-3-indol-3-yl maleimide, 3-1-3-dimethylamino propyl-1h-indol-3-yl-4-1h-indol-3-yl-1h-pyrrole-2,5-dione
PubChem CID 2396
ChEBI CHEBI:41072
IUPAC Name 3-[1-[3-(dimethylamino)propyl]indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
SMILES CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54

Specifications

Color Orange
Quantity 5 mg
Solubility Information Insoluble in water.
Formula Weight 412.48
Physical Form Crystalline Powder
Chemical Name or Material Bisindolylmaleimide 1

RUO – Research Use Only

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