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R&D Systems™ AZ' '9567

Product Code. 31794316
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Quantity:
5 mg
Unit Size:
5mg
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Product Code. Quantity Unit Size
31794316 5 mg 5mg
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Product Code. 31794316 Supplier R&D Systems™ Supplier No. 8897/5
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Estimated Shipment: 02-11-2026
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Description

A Tocris product, part of R&D Systems. Potent MAT2a (methionine adenosyltransferase 2a) inhibitor

AZ'9567 is a potent MAT2a (methionine adenosyltransferase 2a) inhibitor (IC50 = 1.3 nM). AZ'9567 shows strong antiproliferative effect on methylthioadenosine phosphorylase (MTAP) null lymphoma, lung, and pancreatic cancer cell lines and in vivo in MTAP KO HCT116 xenograft mouse model (20 mg/kg twice a day). AZ'9567 is orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-Cyclopropyl-4-[4-(difluoromethoxy)phenyl]-1,4-dihydro-6-(2-methyl-2H-indazol-5-yl)-5H-pyrazolo[4,3-b]pyridin-5-one
CAS 3056570-19-2
Quantity 5 mg
Product Line Tocris
Target Other Transferase Inhibitors
Molecular Formula C24H19F2N5O2
Purity 98%
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