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Paxillin Mouse, Unlabeled, Clone: 177, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 610568
Additional Details : Weight : 0.01000kg
Description
Paxillin, a focal adhesion protein, is a substrate for several tyrosine kinases such as src, FAK, and p120BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. This is consisent with the possibility that paxillin is involved in the regulation of cell morphology. Additionally, because of its SH3-binding domain, paxillin associates tightly with FAK and Crk in an extracellular matrix-independent manner. Although paxillin was initially detected in fibroblasts, its phosphorylation may be important during neurite extension during differentiation.
Specifications
Paxillin | |
Monoclonal | |
250μg/mL | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
50 μg | |
Cell Biology | |
Bovine, Canine, Chicken, Human, Mouse, Rat | |
IgG1 |
Western Blot | |
177 | |
Unconjugated | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.