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STEMCELL Technologies AG-490

Product Code. p-7217587
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. Quantity unitSize
17190142 10 mg 10mg
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Product Code. 17190142 Supplier STEMCELL Technologies Supplier No. 72932

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Description

Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3, and STAT5a/b

  • AG-490 is a member of the tyrphostin family of small molecule inhibitors of tyrosine kinases including EGFR (Gazit et al.), HER2 (Gazit et al.), JAK2 (Burger et al.), JAK3 (Brown et al.), and STAT5a/b (Wang et al.) with IC50 values of 0.1, 13.5, 11 and 12 μM, respectively
  • AG-490 does not inhibit LCK, LYN, BTK, SYK, or SRC tyrosine kinases (Meydan et al.)

Specifications

CAS 133550-30-8
Synonym Tyrphostin AG-490
Quantity 10 mg
Molecular Formula C17H14N2O3
Purity ≥98%
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