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Tocris Bioscience™ (±)-ADX71743, >98%;
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Product Code. 30000878
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30000878

Brand: Tocris Bioscience™ 5715/10

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This item is not returnable. View return policy

Description

Negative allosteric modulator at mGlu7; brain penetrant

Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro. Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 269.34
Purity >98%
Chemical Name or Material 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone
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