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  7. 4',5,7-Trihydroxyflavone, 97%

4',5,7-Trihydroxyflavone, 97%

Product Code. 11358126
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11368126 100 mg 100mg
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Code produit 11358126 Fournisseur Thermo Scientific Alfa Aesar Code fournisseur L15041.MB
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Description

CAS: 520-36-5 | C15H10O5 | 270.24 g/mol

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 520-36-5
Molecular Formula C15H10O5
Molecular Weight (g/mol) 270.24
MDL Number MFCD00006831
InChI Key KZNIFHPLKGYRTM-UHFFFAOYSA-N
Synonym apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
PubChem CID 5280443
ChEBI CHEBI:18388
IUPAC Name 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

Spécification

Melting Point ∽315°C (decomposition)
Quantity 25 mg
Beilstein 262620
Merck Index 14,730
Solubility Information Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
Formula Weight 270.24
Percent Purity 97%
Chemical Name or Material 4',5,7-Trihydroxyflavone

Sécurité et traitement

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Identifiant produit
  • 4',5,7-Trihydroxyflavone
 Mention d'avertissement
  • Warning
 Catégorie de danger
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Mention de danger
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Conseils de prudence
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Informations supplémentaires
  • MIXTURE LIST-Contain: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzo pyrone
FDS

RUO – Research Use Only

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