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Thermo Scientific™ 2'-OMe-U Phosphoramidite, standard grade, 28-400 finish bottle
2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis.
Brand: Thermo Scientific™ 27-1825-11
Additional Details : Weight : 0.05200kg
Description
2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.
Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C40H56N7O9P
• Base: U
• Formula weight: 760.8 g/mol
• CAS number: 110764-79-9
• HPLC purity: ≥98.0%; Sum of non-primary peaks at 140-152ppm: ≤0.5%
• 31P NMR purity: ≥98.0%
Specifications
| MerMade Synthesizers | |
| Store in freezer (at or below -20°C). | |
| 2in-OMe modified | |
| 98% | |
| Phosphoramidite | |
| RNA |
| 2in-OMe-U CEP | |
| Uridine (U) | |
| Room Temperature | |
| 1 g | |
| Standard | |
| Powder |