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Description
- It has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2.
- It may also reduce weight gain in people taking atypical antipsychotics. 1,1-Dimethylbiguanide hydrochloride is suitable biguanide agent used in a study to investigate its role in enhancing the secretions of plasma active glucagon-like peptide-1 (GLP-1) levels.
- 1,1-Dimethylbiguanide, Hydrochloride (Metformin) is a biguanide antihyperglycemic agent. 1,1-Dimethylbiguanide hydrochloride (metformin) is a strong base.
- It forms well defined salts and possessing excellent coordination capacity with transition metals, forming highly colored bidentate chelate complexes.
- Metformin (MET) exists in various forms: diprotonated (H2MET)2+ in strong acidic solution, monoprotonated (HMET)+ in weak acid, MET in neutral and deprotonated (MET)- in strong alkali solution. It is an oral antidiabetic drug.
- Pharmacokinetics of metformin has been studied. Determination of metformin in human plasma has been described by simple HPLC-UV method.[5] Metformin is reported to increase plasma active glucagon-like peptide-1 (GLP-1) in humans
Especificaciones
Especificaciones
| CAS | 1115-70-4 |
| Melting Point | 214°C to 224°C |
| Color | White |
| Molecular Formula | C4H12ClN5 |
| MDL Number | MFCD00012582 |
| Quantity | 25 g |
| Synonym | metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform |
| Solubility Information | Soluble in water (100mg/mL - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform. |
| InChI Key | OETHQSJEHLVLGH-UHFFFAOYSA-N |
| SMILES | [H+].[Cl-].CN(C)C(=N)N=C(N)N |
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Seguridad y manipulación
Nombre del producto
- 1,1-Dimethylbiguanide Hydrochloride
- Warning
- Acute toxicity Category 4
- Serious eye damage/eye irritation Category 2
- Skin corrosion/irritation Category 2
- H302-Harmful if swallowed.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- P264-Wash thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321-Specific treatment (see on this label).
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contains : Metformin Hydrochloride
Título del producto
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