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Expi293 PRO Expression System
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Expi293 PRO Expression System

Next-generation HEK293 platform for high-yield, scalable protein expression.

Why Choose the Gibco™ Expi293TM PRO Expression System?

Maximized Protein Yield

Achieve higher titers with optimized HEK293 cells designed for superior transient expression performance and productivity.

Maximized Protein Yield

Scalable from Bench to Production

Seamlessly transition from small-scale experiments to large-volume production without re-optimization.

Scalable from Bench to Production

Fast, Reliable Results

Accelerate timelines with a streamlined workflow that delivers consistent, reproducible protein expression.

Fast, Reliable Results

Applicable Solutions

Applicable Solutions

Rapid Transient Protein Expression

Accelerate early-stage research with a high-efficiency transient expression system that delivers fast turnaround and high protein yields for screening and discovery.

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High Transfection Efficiency

Optimized chemistry enables robust DNA delivery, maximizing expression across a wide range of constructs.

High-Density Cell Growth

Supports elevated viable cell densities, translating directly into increased protein output per mL.

Serum-Free, Suspension Culture

Simplifies handling and reduces variability, ensuring reproducible results and easy scalability.

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Expi293 PRO Expression System: A Next-Generation Expression System for Higher Yields Across a Wider Variety of Proteins

Poster: Introduction to the next-generation Expi293 PRO Expression System along with the principles and components of the system that allow for higher yields (up to 4g/L), faster expression kinetics, and a scalable and automation-friendly protocol. 

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Automating the Expi293TM PRO Expression System for mAb and Fc Fusion Protein Production

Poster: Automation of small scale, high-throughput protein expression is becoming more critical as artificial intelligence (AI) and machine learning (ML) are increasingly being implemented in the design and optimization of therapeutic protein candidates.

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Automating Expi293TM PRO Expression System for mAb and Fc Fusion Protein Production

Frequently Asked Questions

Expi293 PRO is designed for high-yield transient protein expression in HEK293 cells, ideal for antibody production, protein screening, and early-stage biologics development.

It combines high-density cell growth, optimized transfection, and specialized media to deliver significantly higher protein titers compared to standard HEK293 systems.

Yes, the system is fully scalable from small research volumes to bioreactor-based production without compromising performance or reproducibility.