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  5. Tocris Bioscience™ T3 CLK

Tocris Bioscience™ T3 CLK
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Product Code. 18754434
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18754434

Brand: Tocris Bioscience™ 7570/10

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This item is not returnable. View return policy

Description

Potent and selective pan-CLK inhibitor; also inhibits DYRK1A/B

T3 CLK is a potent and selective pan CDC-like kinase (CLK) inhibitor (IC50 values are 0.67 nM, 15 nM, and 110 nM for CLK1, CLK2, and CLK3 protein kinases, respectively). T3 CLK also inhibits DYRK1A/B (IC50 values are 230 nM and 260 nM for DYRK1B and DYRK1A, respectively in cellular assays). Exhibits dose-dependent alternative splicing effects in HCT116 colorectal cancer cells. T3 CLK is cell permeable, stable and non-toxic.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 4-[1,1-Dimethyl-2-(4-methyl-1-piperazinyl)-2-oxoethyl]-N-[6-(4-pyridinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
CAS 2109805-56-1
Quantity 10 mg
Target Cdc2-like Kinase Inhibitors
Molecular Formula C28H30N6O2
Purity 0.98
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