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MP Biomedicals™ Collagenase Type II from Clostridium histolyticum
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Quantity:
1 g
Unit Size:
1g
Description
Collagenase degrades native helical collagen fibrils. It has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. It is a type II enzyme that contains greater clostripain activity.
- Specific activity:> 125 units/mg solid
- Unit definition: Liberates one μmole of L-leucine equivalents from collagen in 5 hours at 37°C, pH 7.5
- Presentation: brown shiny flakes
- Format: lyophilized powder
- pH: 7-9 for the A-a enzyme (optimum pH)
- Solubility: Soluble in water
- Pack size: 1g
Specifications
Specifications
| Concentration | 1 mg/mL |
| Color | Brown |
| pH | 7 to 9 |
| For Use With (Application) | Collagen structural and biosynthetic studies, release of cells from animal tissues |
| Storage Buffer | 1mg/mL of Enzyme in 0.05M TES with 0.36mM Calcium Chloride, pH 7.5 |
| Content And Storage | 4°C |
| Source | Clostridium histolyticum |
| Quantity | 1 g |
| Product Type | Collagenase Type II |
| Molecular Weight (g/mol) | 105000 and 57400 |
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Safety and Handling
Signal Word
- Danger
- Skin corrosion/irritation Category 2
- Respiratory sensitiser Category 1
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H335-May cause respiratory irritation.
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- P321-Specific treatment (see on this label).
- P501-Dispose of contents/container to in accordance with local/regional/national/international regulations.
- P284-¢In case of inadequate ventilation! wear respiratory protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P101-If medical advice is needed, have product container or label at hand.
- P103-Read label before use.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P102-Keep out of reach of children.
- P405-Store locked up.
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