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Abnova™ Human TYROBP Full-length ORF (NP_003323.1, 1 a.a. - 113 a.a.) Recombinant Protein with GST-tag at N-terminal

Used for AP, Array, ELISA, WB-Re

335.00€ - 508.00€

Specifications

Accession Number NP_003323.1
Formulation 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene ID (Entrez) 7305
Molecular Weight (g/mol) 38.6kDa
Purification Method Glutathione Sepharose 4 Fast Flow
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Product Code Brand Quantity Price Quantity & Availability  
16103908
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Abnova™
H00007305-P01.25UG
25 ug
508.00€
25µg
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16193898
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Abnova™
H00007305-P01.10UG
10μg
335.00€
10µg
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Estimated Shipment: 31-05-2024
to see stock.
Add to basket
 
Description

Description

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Two alternative transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described, but their full-length nature has not been deterimined. [provided by RefSeq]

Sequence: MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLAGIVMGDLVLTVLIALAVYFLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
Specifications

Specifications

NP_003323.1
7305
Glutathione Sepharose 4 Fast Flow
RUO
TYROBP
Recombinant
Liquid
50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer.
38.6kDa
12.5% SDS-PAGE Stained with Coomassie Blue.
TYROBP
Wheat Germ (in vitro)
wheat germ expression system
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