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ACROBiosystems Human TYRO3 / Dtk Protein, Fc Tag

Brand:  ACROBiosystems TY3-H5251-200UG

Additional Details : Weight : 0.00001kg

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Product Code. 15807887

  • 302.64€ / 200µg


Estimated Shipment: 19-10-2021
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Description

Description

Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 68.2 kDa. The protein migrates as 86-106 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

AAH51756.1 (Q261H)
HEK293
Human
68.2 kDa
200 µg
Ala 41 - Ser 428
TYRO3,BYK,DTK,RSE,SKY,TIF
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human TYRO3, Fc Tag (TY3-H5251) is expressed from human 293 cells (HEK293). It contains AA Ala 41 - Ser 428 (Accession # AAH51756.1 (Q261H)).
-20°C
TYRO3
Fc Tag
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