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ACROBiosystems Human Serpin F1 / PEDF Protein, His Tag

Brand:  ACROBiosystems SE1-H5221-1MG

Additional Details : Weight : 0.00001kg

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Product Code. 15817667

  • 1815.83€ / 1mg


Estimated Shipment: 25-10-2021
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Description

Description

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.2 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_002606
HEK293
Human
45.2 kDa
1 mg
Gln 20 - Pro 418
SERPINF1,Serpin F1,PEDF,PIG35,EPC-1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human Serpin F1, His Tag (SE1-H5221) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Pro 418 (Accession # NP_002606).
-20°C
Serpin F1
His Tag
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