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ACROBiosystems Human R-Spondin 1 / RSPO1 Protein, His Tag
457.25€ - 4350.40€
Specifications
| Accession Number | NP_001033722.1 |
|---|---|
| Molecular Weight (g/mol) | 28.7 kDa |
| Source | Human R-Spondin 1, His Tag (RS1-H4221) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Ala 263 (Accession # Q2MKA7-1). |
| Immunogen | Ser 21 - Ala 263 |
| Storage Requirements | -20°C |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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15817627
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ACROBiosystems
RS1-H4221-50UG |
50 μg |
457.25€
50µg |
Estimated Shipment: 26-04-2024
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|
15807627
|
ACROBiosystems
RS1-H4221-1MG |
1 mg |
4350.40€
1mg |
Estimated Shipment: 26-04-2024
Log in to see stock. |
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Description
R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.7 kDa. The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| NP_001033722.1 | |
| Human R-Spondin 1, His Tag (RS1-H4221) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Ala 263 (Accession # Q2MKA7-1). | |
| -20°C | |
| R-Spondin 1 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 28.7 kDa | |
| Ser 21 - Ala 263 | |
| RSPO1,CRISTIN3,FLJ40906,RP11-566C13.1,R-spondin-1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |