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ACROBiosystems Human Osteoactivin / GPNMB Protein, His Tag

Brand:  ACROBiosystems GPB-H5229-1MG

Additional Details : Weight : 0.00001kg

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Product Code. 15816897

  • 1614.07€ / 1mg


Estimated Shipment: 22-10-2021
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Description

Description

Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.4 kDa. The protein migrates as 85-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

AAH32783
HEK293
Human
53.4 kDa
1 mg
Ala 22 - Pro 486
GPNMB,HGFIN,NMB,Osteoactivin
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human Osteoactivin, His Tag (GPB-H5229) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Pro 486 (Accession # AAH32783).
-20°C
Osteoactivin
His Tag
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