missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human Nectin-3 / CD113 Protein, His Tag

Brand:  ACROBiosystems PV3-H52E4-100UG

Additional Details : Weight : 0.00001kg

 View more versions of this product

Product Code. 15817577

  • 302.64€ / 100µg


Estimated Shipment: 27-10-2021
Add to basket

Description

Description

Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin system in epithelial cells. PVRL3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Furthermore, PVRL3 induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.6 kDa. The protein migrates as 55-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

Q9NQS3
HEK293
Human
39.6 kDa
100 µg
Gly 58 - Asp 400
CD113,Nectin-3,PVRL3
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human Nectin-3, His Tag (PV3-H52E4) is expressed from human 293 cells (HEK293). It contains AA Gly 58 - Asp 400 (Accession # Q9NQS3).
-20°C
Nectin-3
His Tag
Videos
SDS
Documentos
Certificados