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ACROBiosystems Human LILRB3 / CD85a / ILT5 Protein, His tag
Brand: ACROBiosystems CDA-H52H9-1MG
Additional Details : Weight : 0.00001kg
Description
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48 kDa. The protein migrates as 60-78 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| AAB68668 (P288R) | |
| 1 mg | |
| Gly 24 - Glu 443 | |
| LILRB3,CD85a,ILT5 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >92% as determined by SDS-PAGE |
| 48 kDa | |
| Human LILRB3, His Tag (CDA-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R)). | |
| -20°C | |
| LILRB3 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |