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ACROBiosystems Human LILRB2 / CD85d / ILT4 Protein, His Tag
Brand: ACROBiosystems LI2-H5220-1MG
Additional Details : Weight : 0.00001kg
Description
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 58-67 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| AAH36827 | |
| 1 mg | |
| Gln 22 - Val 461 | |
| LILRB2,ILT4,LIR2,MIR10,CD85d | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 48.6 kDa | |
| Human LILRB2, His Tag (LI2-H5220) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Val 461 (Accession # AAH36827). | |
| -20°C | |
| LILRB2 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Immune Checkpoint Proteins |