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ACROBiosystems Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free

Brand:  ACROBiosystems IT1-H52W5-1MG

Additional Details : Weight : 0.00001kg

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Product Code. 15807147

  • 2905.32€ / 1mg


Estimated Shipment: 20-10-2021
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Description

Description

Integrin alpha 5 beta 1 / Integrin α5β1, which is a major cellular receptor for the extracellular matrix protein fibronectin and plays a fundamental role during mammalian development., is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. Integrins are adhesion receptors that transmit bidirectional signals across the plasma membrane. The Integrin alpha 5 beta 1 and its primary extracellular matrix ligand fibronectin (Fn) are of great biological importance.

Human ITGA5&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA5 and ITGB1, has a calculated MW of 110.7 kDa (ITGA5) and 83.7 kDa (ITGB1). Subunit ITGA5 is fused with an acidic tail at the C-terminus and followed by a polyhistid
Specifications

Specifications

NP_002196.4 (ITGA5) and NP_002202.2 (ITGB1)
HEK293
Human
110.7 kDa (ITGA5) and 83.7 kDa (ITGB1)
1 mg
Phe 42 - Tyr 995 (ITGA5) and Gln 21 - Asp 728 (ITGB1)
Integrin alpha 5 beta 1,ITGA5andITGB1
Unconjugated
50 mM Tris, 150 mM NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human ITGA5&ITGB1; Heterodimer Protein, His Tag&Tag; Free (IT1-H52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 42 - Tyr 995 (ITGA5) and Gln 21 - Asp 728 (ITGB1) (Accession # P08648-1 (ITGA5) and P05556-1 (ITGB1)).
-20°C
Integrin alpha 5 beta 1
His Tag
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