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ACROBiosystems Human Integrin alpha 5 beta 1 (ITGA5&ITGB1) Heterodimer Protein, His Tag&Tag Free
Brand: ACROBiosystems IT1-H52W5-1MG
Additional Details : Weight : 0.00001kg
Description
Integrin alpha 5 beta 1 / Integrin α5β1, which is a major cellular receptor for the extracellular matrix protein fibronectin and plays a fundamental role during mammalian development., is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. Integrins are adhesion receptors that transmit bidirectional signals across the plasma membrane. The Integrin alpha 5 beta 1 and its primary extracellular matrix ligand fibronectin (Fn) are of great biological importance.
Human ITGA5&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA5 and ITGB1, has a calculated MW of 110.7 kDa (ITGA5) and 83.7 kDa (ITGB1). Subunit ITGA5 is fused with an acidic tail at the C-terminus and followed by a polyhistidSpecifications
NP_002196.4 (ITGA5) and NP_002202.2 (ITGB1) | |
1 mg | |
Phe 42 - Tyr 995 (ITGA5) and Gln 21 - Asp 728 (ITGB1) | |
Integrin alpha 5 beta 1,ITGA5andITGB1 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
110.7 kDa (ITGA5) and 83.7 kDa (ITGB1) | |
Human ITGA5&ITGB1; Heterodimer Protein, His Tag&Tag; Free (IT1-H52W5) is expressed from human 293 cells (HEK293). It contains AA Phe 42 - Tyr 995 (ITGA5) and Gln 21 - Asp 728 (ITGB1) (Accession # P08648-1 (ITGA5) and P05556-1 (ITGB1)). | |
-20°C | |
Integrin alpha 5 beta 1 | |
Human | |
50 mM Tris, 150 mM NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |