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ACROBiosystems Human IgG1 Fc Protein, His Tag

Brand:  ACROBiosystems IG1-H5225-200UG

Additional Details : Weight : 0.00001kg

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Product Code. 15816987

  • 262.28€ / 200µg


Estimated Shipment: 20-10-2021
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Description

Description

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.9 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human IgG Fc, His Tag (IG1-H5225) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1).
-20°C
IgG1 Fc
His Tag
HEK293
Human
26.9 kDa
200 µg
Glu 99 - Lys 330
IgG1
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
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