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ACROBiosystems Human IFN-alpha/beta R2 Protein, His Tag

Brand:  ACROBiosystems IF2-H5224-1MG

Additional Details : Weight : 0.00001kg

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Product Code. 15816977

  • 1614.07€ / 1mg


Estimated Shipment: 19-10-2021
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Description

Description

Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFN-alpha binding protein, IFN-alpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 34-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_997467.1
HEK293
Human
25.8 kDa
1 mg
Ile 27 - Lys 243
IFNAR2,IFNARB,IFNABR,IFN-R-2,IFN-alpha/beta receptor 2
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human IFNAR2, His Tag (IF2-H5224) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Lys 243 (Accession # P48551-2).
-20°C
IFN-alpha/beta R2
His Tag
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