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ACROBiosystems Human FGF acidic Protein, Tag Free

Brand:  ACROBiosystems AFF-H4116-1MG

Additional Details : Weight : 0.00001kg

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Product Code. 15825897

  • 706.15€ / 1mg


Estimated Shipment: 22-10-2021
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Description

Description

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

This protein carries no "e;tag"e;. The protein has a calculated MW of 16.0 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
Specifications

Specifications

NP_000791.1
E.coli
Human
16.0 kDa
1 mg
Phe 16 - Asp 155
FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Cytokines and Growth Factors
Powder
>98% as determined by SDS-PAGE
Human FGF acidic, Tag Free (AFF-H4116) is expressed from E.coli cells. It contains AA Phe 16 - Asp 155 (Accession # P05230-1).
-20°C
FGF acidic
Tag Free
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