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ACROBiosystems Human FGF acidic Protein, Tag Free

233.21€ - 1010.59€

Specifications

Accession Number NP_000791.1
Molecular Weight (g/mol) 16.0 kDa
Source Human FGF acidic, Tag Free (AFF-H4116) is expressed from E.coli cells. It contains AA Phe 16 - Asp 155 (Accession # P05230-1).
Immunogen Phe 16 - Asp 155
Storage Requirements -20°C
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Product Code Brand Quantity Price Quantity & Availability  
15825897
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ACROBiosystems
AFF-H4116-1MG
1 mg
1010.59€
1mg
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15835897
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ACROBiosystems
AFF-H4116-200UG
200 μg
233.21€
200µg
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Description

Description

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

This protein carries no “tag”. The protein has a calculated MW of 16.0 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).
Specifications

Specifications

NP_000791.1
Human FGF acidic, Tag Free (AFF-H4116) is expressed from E.coli cells. It contains AA Phe 16 - Asp 155 (Accession # P05230-1).
-20°C
FGF acidic
Human
PBS, pH7.4
E.coli
Cytokines and Growth Factors
16.0 kDa
Phe 16 - Asp 155
FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1
Unconjugated
Tag Free
Less than 1.0 EU / μg by the LAL method.
Powder
>98% as determined by SDS-PAGE
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