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ACROBiosystems Human DNAM-1 / CD226 Protein, His Tag

Brand:  ACROBiosystems DN1-H52H6-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15816587

  • 252.20€ / 100µg


Estimated Shipment: 25-10-2021
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Description

Description

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ∼65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 36-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_006557
HEK293
Human
27.9 kDa
100 µg
Glu 19 - Asn 247
DNAM1,CD226,PTA1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human DNAM-1, His Tag (DN1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).
-20°C
DNAM-1
His Tag
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