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ACROBiosystems Human CXADR / CAR Protein, His Tag

Brand:  ACROBiosystems CXR-H5222-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15816557

  • 252.20€ / 100µg


Estimated Shipment: 19-10-2021
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Description

Description

Coxsackie virus and adenovirus receptor (CXADR) is also known as CAR, is a type I transmembrane glycoprotein for group B coxsackie viruses and subgroup C adenoviruses, and belongs to the CTX family of the Ig superfamily. CAR is strongly expressed in the developing central nervous system. It functions as a homophilic and also as a heterophilic cell adhesion molecule through its interactions with extracellular matrix glycoproteins such as: fibronectin, agrin, laminin-1 and tenascin-R. Human CXADR protein contains a signal sequence, a extracellular domain (ECD) with a V­ type (D1) and a C2­ type (D2) Ig­like domain, a transmembrane segment and a intracellular domain. D1 is thought to be responsible for homodimer formation in trans within tight junctions, and is necessary and sufficient for adenovirus binding. Variants of CXADR are attached to the cell membrane by a GPI- anchor.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.9 kDa. The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001329.1
HEK293
Human
24.9 kDa
100 µg
Leu 20 - Gly 237
CXADR,CAR,CAR4/6,HCAR
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human CXADR, His Tag (CXR-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Gly 237 (Accession # NP_001329.1).
-20°C
CXADR
His Tag
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