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ACROBiosystems Human CD38 Protein, Fc Tag

MALS verified

Brand:  ACROBiosystems CD8-H5255-50UG

Additional Details : Weight : 0.00001kg

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Product Code. 15816307

  • 292.55€ / 50µg


Estimated Shipment: 20-10-2021
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Description

Description

CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.5 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001766.2
HEK293
Human
56.5 kDa
50 µg
Val 43 - Ile 300
CD38,T10,cADPr hydrolase 1
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human CD38, Fc Tag (CD8-H5255) is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300 (Accession # P28907-1).
-20°C
CD38
Fc Tag
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