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ACROBiosystems Human CD30 / TNFRSF8 Protein, His Tag

MALS verified

Brand:  ACROBiosystems CD0-H5229-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15816127

  • 262.28€ / 100µg


Estimated Shipment: 19-10-2021
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Description

Description

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.3 kDa. The protein migrates as 53-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_001234.2
HEK293
Human
39.3 kDa
100 µg
Phe 19 - Lys 379
TNFRSF8,CD30,D1S166E,Ki-1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>90% as determined by SDS-PAGE
Human CD30, His Tag (CD0-H5229) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
-20°C
CD30
His Tag
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