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ACROBiosystems Human CADM1 / IGSF4A Protein, His Tag

Brand:  ACROBiosystems CA1-H5225-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15826087

  • 262.28€ / 100µg


Estimated Shipment: 19-10-2021
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Description

Description

Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. Cell adhesion molecule 1 is a single-pass type I membrane protein which belongs to the nectin family. Cell Adhesion Molecule 1 contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain, and is also known as CADM1; BL2; DKFZp686F1789; IGSF4; IGSF4A; MGC149785; MGC51880; NECL2; Necl-2; RA175; ST17; SYNCAM; TSLC1; sTSLC-1; sgIGSF; synCAM1. CADM1 mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. CADM1 may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. CADM1 may play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.9 kDa. The protein migrates as 50 kDa and 55-85 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
Specifications

Specifications

NP_055148.3
HEK293
Human
37.9 kDa
100 µg
Gln 45 - His 374
CADM1,BL2,IGSF4,IGSF-4,IGSF4A,NECL2,Necl-2,RA175,ST17,SYNCAM,TSLC1,sTSLC-1,sgIGSF,synCAM1,DKFZp686F1789,MGC149785,MGC51880
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human CADM1, His Tag (CA1-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 45 - His 374 (Accession # NP_055148.3).
-20°C
CADM1
His Tag
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