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ACROBiosystems Human BMPR-IA / ALK-3 Protein, Fc Tag
Brand: ACROBiosystems AL3-H5259-1MG
Additional Details : Weight : 0.00001kg
Description
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2[1]. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 56 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifications
| CAA80257 | |
| 1 mg | |
| Gln 24 - Arg 152 | |
| BMPR-1 A,ALK-3,10q23del,ACVRLK3,CD292,SKR5 | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >98% as determined by SDS-PAGE |
| 40.3 kDa | |
| Human BMPR-IA, Fc Tag (AL3-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Arg 152 (Accession # P36894-1). | |
| -20°C | |
| BMPR-IA | |
| Human | |
| 50 mM Tris, 100 mM Glycine, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |