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ACROBiosystems Human Bcl-x / BCL2L1 Protein, GST Tag

Brand:  ACROBiosystems BC1-H513A-100UG

Additional Details : Weight : 0.00001kg

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Product Code. 15826017

  • 252.20€ / 100µg


Estimated Shipment: 20-10-2021
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Description

Description

Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE).
Specifications

Specifications

AAH19307
E.coli
Human
50.6 kDa
100 µg
Ser 2 - Arg 212
BCL2L1,Bcl-XL,Bcl2-L-1,BCL-XL/S,BCL2L,BCLX,BCLXL,BCLXS,Bcl-X,bcl-xS
Unconjugated
20 mM Tris, 100 mM NaCl, pH7.5 with 10 mM GSH
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>92% as determined by SDS-PAGE
Human Bcl-x, GST Tag (BC1-H513a) is expressed from E.coli cells. It contains AA Ser 2 - Arg 212 (Accession # AAH19307).
-20°C
Bcl-x
GST Tag
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